Comparing clinical and imaging features of patients with MOG antibody-positivity and with and without oligoclonal bands

Introduction Myelin-oligodendrocyte glycoprotein antibody (MOG)–associated disorder (MOGAD) is a recently identified immune-mediated inflammatory of the central nervous system (CNS). The significance oligoclonal bands (OCBs) not fully elucidated. This study investigated clinical differences between patients with MOGAD who tested positive or negative for OCBs. Methods was conducted on 23 MOG-IgG-seropositivity presented (CNS) symptoms. were screened and divided into OCB-positive (n=10) OCB-negative (n=13) groups, their demographic, clinical, magnetic resonance imaging (MRI) features compared. Results results revealed that OCB-positivity had significantly higher frequency relapse, IgG index higher. Discussion OCBs common in met consensus criteria. concluded careful treatment decision-making necessary MOG antibody-positive cases OCB-positivity.